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Gonorrhea rates are increasing about 10 to 20% each year over the last three years in Australia and elsewhere. The Communicable Diseases Network Australia: 2 Aug 13
The extensively drug resistant strains of Gonorrhea that have been reported so far in places like France and Japan are simply a slight variant of a multi-drug resistant clone that appears to have spread very quickly throughout the world over the last 10 years. So it is very likely that a super drug resistant or XDR strain of gonorrhea will arrive sooner or later. The Communicable Diseases Network Australia: 2 Aug 13
Gonococcus, with high level of resistance to the antibiotic azithromycin, is identified in Hawaii, USA. (Gonococci cause gonorrhea) Clinical Infectious Diseases 2012 Mar 15; 54:841
Gonorrhea super bug: Neisseria gonorrhea H041, a new strain of gonococci which causes gonorrhea is resistant to cephalosporins, the current treatment of choice. International Society for Sexually Transmitted Disease Research Conference July 2011, Quebec City, Canada
Cefixime is no longer recommended as first choice in the gonorrhea. Reduced susceptibility to Cefixime is observed in 17.4 % of cases gonorrhea. According to WHO, when treatment failure reaches 5%, the first-line antibiotic used should be changed.
Centre for Diseases Control, USA has recommended a change in the treatment of Gonorrhea: Ceftriaxone 250 mg injection and Azithromycin 1 g orally is the most effective treatment for uncomplicated gonorrhea. The change is in view of the increasing resistance of gonococci to cephalosporin. CDC MMWR July 8, 2011 / 60(26); 873
Asymptomatic throat infection with gonococci acts as reservoir sustaining the community prevalence of gonorrhea. Sexually Transmitted Infections November 2010; 86 (6)
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